Message Passing Interface (MPI) is a popular approach to enable Single Process, Multiple Data (SPMD) style parallel computing, particularly in cluster computing environments. Communicating Process Architecture (CPA) Networking on the other hand, has been developed to enable channel based semantics across a communication mechanism in a transparent manner. However, in both cases the concept of a message passing infrastructure is fundamental. This paper compares the performance of both of these frameworks at a base communication level, also discussing some of the similarities between the two mechanisms. From the experiments, it can be seen that although MPI is a more mature technology, in many regards CPA Networking can perform comparably if the correct communication is used.